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PKC alpha Antikörper (pThr638)

Name: PKC alpha Antikörper (pThr638)
SKU: ABIN1531462
Price: 402 EUR
Availability: InStock

PKCa Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts from NIH-3T3 cells treated with UV 15', using PKC alpha (Phospho-Thr638) Antibody.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using PKC alpha (Phospho-Thr638) Antibody.

IHC

2 Abbildungen

(1 reference)

Produktnummer ABIN1531462

Datenblatt (PDF)

Target Alle PKC alpha (PKCa) Antikörper anzeigen

PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
Bindungsspezifität
22

20

18

12

11

10

8

7

7

6

6

5

5

5

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 606-655, pThr638
Reaktivität
179

92

70

6

6

5

5

3

3

2

2

1

1

1

1
Human, Maus, Ratte
Wirt
171

16

1
Kaninchen
Passende Sekundärantikörper
Klonalität
139

48
Polyklonal
Konjugat
95

15

13

7

7

6

6

6

6

6

6

6

2

2

1

1

1

1

1
Dieser PKC alpha Antikörper ist unkonjugiert
Applikation
127

70

53

33

23

20

19

15

14

8

5

2

2

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität

PKC alpha (Phospho-Thr638) Antibody detects endogenous levels of PKC alpha only when phosphorylated at Thr638.
PhosphorylationH:T638 M:T638 R:T638

Aufreinigung

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Reinheit

> 95 %

Immunogen

The antiserum was produced against synthesized peptide derived from human PKC alpha around the phosphorylation site of Thr638.

Isotyp

IgG

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anti-Protein Kinase C, alpha (PKCa) (pThr638) antibody
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PKCa Reaktivität: Human, Maus, Ratte, Hund, Huhn, Frosch WB, IHC, IP, IF Wirt: Maus Monoclonal 3-PKCalpha unconjugated

anti-Protein Kinase C, alpha (PKCa) (N-Term) antibody
PKCa Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Kommentare

Unigene-Number: Hs.531704, Hs.708867 (NCBI Gene Symbol: PRKCA)

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Stable at -20°C for at least 1 year.

Haltbarkeit

12 months
Huang, Cheng, Su, Lin: "Syndecan-4 Promotes Epithelial Tumor Cells Spreading and Regulates the Turnover of PKC? Activity under Mechanical Stimulation on the Elastomeric Substrates." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 4, pp. 1291-1304, (2015) (PubMed).
Target

PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Andere Bezeichnung

PKC alpha (PKCa Produkte)

Synonyme

pkc-alpha antikoerper, pkcalpha antikoerper, im:7139045 antikoerper, si:dkey-8l19.1 antikoerper, LOC100219195 antikoerper, AAG6 antikoerper, PKC-alpha antikoerper, PKCA antikoerper, PRKACA antikoerper, AI875142 antikoerper, Pkca antikoerper, PKRCA antikoerper, protein kinase C alpha antikoerper, protein kinase C, alpha L homeolog antikoerper, protein kinase C, alpha antikoerper, PRKCA antikoerper, prkca.L antikoerper, prkca antikoerper, Prkca antikoerper

Hintergrund

Synonyms: kinase PKC-alpha, KPCA, PKC III, PKC-A, PKC-alpha, PKC-III, PRKACA, PRKCA, Protein kinase C, alpha type
NCBI Gene Symbol: PRKCA

Molekulargewicht

76 kDa

Gen-ID

5578

OMIM

176960

UniProt

P17252

Pathways

WNT Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling