PCLO Antikörper (PE)

Produktnummer ABIN1526067

Produktdetails anti-PCLO Antikörper (PE)

Target: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PCLO Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Size-exclusion chromatography

Klon: PCLO-01

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: Phosphate buffered saline (PBS), 15 mM sodium azide, 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu PCLO

Target: PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))

Andere Bezeichnung: PCLO (PCLO Produkte)

Synonyme: pclo antikoerper, wu:fj53e09 antikoerper, Acz antikoerper, Pico antikoerper, mKIAA0559 antikoerper, aczonin antikoerper, PCLO antikoerper, ACZ antikoerper, piccolo presynaptic cytomatrix protein antikoerper, piccolo presynaptic cytomatrix protein a antikoerper, piccolo (presynaptic cytomatrix protein) antikoerper, PCLO antikoerper, pcloa antikoerper, Pclo antikoerper, LOC768552 antikoerper

Hintergrund: PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion.Synonyms: ACZ, Aczonin, KIAA0559, Protein piccolo

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis