MPZ Antikörper

Produktnummer ABIN1513218

Produktdetails anti-MPZ Antikörper

Target: MPZ (Myelin Protein Zero (MPZ))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant protein of human MPZ

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MPZ

Target: MPZ (Myelin Protein Zero (MPZ))

Andere Bezeichnung: MPZ (MPZ Produkte)

Synonyme: CHM antikoerper, CMT1 antikoerper, CMT1B antikoerper, CMT2I antikoerper, CMT2J antikoerper, CMT4E antikoerper, CMTDI3 antikoerper, CMTDID antikoerper, DSS antikoerper, HMSNIB antikoerper, MPP antikoerper, P0 antikoerper, Mpp antikoerper, P-zero antikoerper, p0 antikoerper, sc:d0186 antikoerper, wu:fc04b11 antikoerper, wu:fi30g06 antikoerper, zgc:103775 antikoerper, myelin protein zero antikoerper, myelin protein zero S homeolog antikoerper, MPZ antikoerper, Mpz antikoerper, mpz antikoerper, mpz.S antikoerper

Hintergrund: This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies, such as Dejerine-Sottas syndrome (DSS) and congenital hypomyelinating neuropathy (CHN). A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism.,MPZ,CHM,CMT1,CMT1B,CMT2I,CMT2J,CMT4E,CMTDI3,CMTDID,DSS,HMSNIB,MPP,P0,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Neuron marker,Axon marker,MPZ

Molekulargewicht: 27 kDa/34 kDa

Gen-ID: 4359

UniProt: P25189