Dynamitin Antikörper (AA 50-320)

Produktnummer ABIN1512818

Produktdetails anti-Dynamitin Antikörper

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Bindungsspezifität: AA 50-320

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamitin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: HIIVNPNAAY DKFKDKRVGT KGLDFSDRIG KTKRTGYESG EYEMLGEGLG VKETPQQKYQ RLLHEVQELT TEVEKIKTTV KESATEEKLT PVLLAKQLAA LKQQLVASHL EKLLGPDAAI NLTDPDGALA KRLLLQLEAT KNSKGGSGGK TTGTPPDSSL VTYELHSRPE QDKFSQAAKV AELEKRLTEL ETAVRCDQDA QNPLSAGLQG ACLMETVELL QAKVSALDLA VLDQVEARLQ SVLGKVNEIA KHKASVEDAD TQSKVHQLYE T

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human DCTN2 (NP_006391.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:20 - 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Dynamitin

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Andere Bezeichnung: DCTN2 (DCTN2 Produkte)

Synonyme: DCTN2 antikoerper, dctn2 antikoerper, dctn50 antikoerper, dynamitin antikoerper, rbp50 antikoerper, CG8269 antikoerper, DMN antikoerper, Dmel\\CG8269 antikoerper, P50 antikoerper, dDyn antikoerper, dmn antikoerper, dyna antikoerper, l(2)k16109 antikoerper, l(2)k16218 antikoerper, p50 antikoerper, p50/Dmn antikoerper, p50/dynamitin antikoerper, 2310042E05Rik antikoerper, C130077D06Rik antikoerper, C87049 antikoerper, DCTN-50 antikoerper, GMP23-48K antikoerper, RBP50 antikoerper, DCTN50 antikoerper, DYNAMITIN antikoerper, zgc:63867 antikoerper, dynactin subunit 2 antikoerper, dynactin subunit 2 S homeolog antikoerper, Dynactin 2, p50 subunit antikoerper, dynactin 2 antikoerper, dynactin 2 (p50) antikoerper, dynactin subunit 2 L homeolog antikoerper, DCTN2 antikoerper, dctn2.S antikoerper, DCTN2-p50 antikoerper, dctn2 antikoerper, Dctn2 antikoerper, dctn2.L antikoerper

Hintergrund: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,DCTN2,DCTN50,DYNAMITIN,HEL-S-77,RBP50,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Motor Proteins,Neuroscience,Neurodegenerative Diseases,DCTN2

Molekulargewicht: 44 kDa

Gen-ID: 10540

UniProt: Q13561

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization