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SPINK7/ECRG2 Antikörper (C-Term)
SPINK7
Reaktivität: Human, Maus, Ratte
WB, IHC (p), EIA
Wirt: Huhn
Polyclonal
unconjugated
Produktnummer ABIN1450063
Produktdetails anti-SPINK7/ECRG2 Antikörper
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Target
Alle SPINK7/ECRG2 (SPINK7) Antikörper anzeigen
SPINK7/ECRG2 (SPINK7)
(Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7))
Bindungsspezifität
Alle Epitope für SPINK7/ECRG2 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für SPINK7/ECRG2 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für SPINK7/ECRG2 Antikörper
Huhn
Klonalität
Alle Klonalitäten für SPINK7/ECRG2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für SPINK7/ECRG2 Antikörper
Dieser SPINK7/ECRG2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SPINK7/ECRG2 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Kreuzreaktivität (Details)
Species reactivity (tested):Human, Mouse, Rat.
Aufreinigung
Affinity chromatography purified via peptide column
Immunogen
16 amino acid synthetic peptide near the carboxy terminus of Human ECRG2
Top Product
Discover our top product SPINK7 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu SPINK7/ECRG2
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Target
SPINK7/ECRG2 (SPINK7)
(Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7))
Andere Bezeichnung
ECRG-2 (SPINK7 Produkte )
Synonyme
Ecg2 antikoerper, Ecrg2 antikoerper, OM antikoerper, ECG2 antikoerper, ECRG2 antikoerper, EG408198 antikoerper, serine peptidase inhibitor, Kazal type 7 antikoerper, serine peptidase inhibitor, Kazal type 7 (putative) antikoerper, Spink7 antikoerper, SPIK7 antikoerper, SPINK7 antikoerper
Hintergrund
The esophageal cancer-susceptibility gene 2 (ECRG2), also known as SPINK7, is a novel tumor suppressor gene identified from the human esophagus. It interacts directly with metallothionein 2A and urokinase-type plasminogen activator (uPA), and downregulates the activity of uPA, leading to reduced cancer cell migration, invasion and metastasis. ECRG2 forms a complex with uPA and its receptor uPAR, modifying the dynamic association of uPAR with beta1 integrins and disrupting the Src/MAP kinase pathway that normally stimulates cell migration and invasion. ECRG2 may thus represent a novel therapeutic target for cancer.Synonyms: ECG2, Esophagus cancer-related gene 2 protein, MGC133105, MGC133106, SPINK7, Serine protease inhibitor Kazal-type 7, UNQ745/PRO1474
Gen-ID
84651
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