MUC2 Antikörper

Produktnummer ABIN1449424

Produktdetails anti-MUC2 Antikörper

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUC2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody stains normal colon and colonic carcinomas where it produces intense perinuclear staining in goblet cells. It also reacts with normal and neoplastic breast tissues and with prostate carcinoma. Cellular localization: Cytoplasmic, perinuclear staining of goblet cells.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung: Protein A Chromatography.

Immunogen: Synthetic MUC2 (23 aa) tandem repeat consensus sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears). For IHC dilute concentared antibody at 1/50-1/200 using streptavidin-Biotin system orpolymer system. For FFPE tissue sections high temperature antigen retriever (boiling tissue in 10 mM Citratebuffer for 10 min) enhances the signal and may require further dilution of antibody. Positive Control: Human colon carcinoma, LS 174 T colon cancer cell line.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 2.0 mg/mL

Buffer: 10 mM PO4, 200 mM NaCl, pH 7.4 containing 0.05 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu MUC2

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Andere Bezeichnung: Mucin-2 (MUC2 Produkte)

Synonyme: 2010015E03Rik antikoerper, MCM antikoerper, wnn antikoerper, MLP antikoerper, MUC-2 antikoerper, SMUC antikoerper, HH-Muc antikoerper, mucin 2 antikoerper, mucin 2, oligomeric mucus/gel-forming antikoerper, mucin-2 antikoerper, Muc2 antikoerper, MUC2 antikoerper, LOC100724045 antikoerper

Hintergrund: Mucin 2, oligomeric mucus/gel-forming, also known as MUC2, is a human intestinal mucin gene. This gene is expressed in colon, small intestine, colonic tumors, bronchus, cervix, gall bladder, and possibly other tissues. Mucins are high molecular weight glycoproteins having oligosaccharides attached to serine or threonine residue of the apomucin protein backbone by O-glycosidic linkages.Synonyms: Intestinal mucin-2, MUC-2, MUC2, SMUC

Gen-ID: 4583

NCBI Accession: NP_002448

UniProt: Q02817