IL18R1 Antikörper (Extracellular Domain, N-Term)

Produktnummer ABIN1449294

Produktdetails anti-IL18R1 Antikörper

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Bindungsspezifität: AA 1-329, Extracellular Domain, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL18R1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody detects IL-18R1.

Kreuzreaktivität (Details): Species reactivity (tested):Human (KG-1). Does not react with Mouse transfected cells.

Aufreinigung: Protein A agarose

Immunogen: Human IL-18R1 extracellular domain corresponding to amino acids 1-329

Klon: 44G6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Details zu IL18R1

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Andere Bezeichnung: CD218a / IL18R1 (IL18R1 Produkte)

Synonyme: CD218a antikoerper, CDw218a antikoerper, IL-1Rrp antikoerper, IL18RA antikoerper, IL1RRP antikoerper, IL-1R9 antikoerper, IL1R9 antikoerper, IL1RAPL-2 antikoerper, TIGIRR-1 antikoerper, Il18ralpha antikoerper, Il1rrp antikoerper, IL-18Ra antikoerper, IL18R1 antikoerper, interleukin 18 receptor 1 antikoerper, interleukin 1 receptor accessory protein like 2 antikoerper, IL18R1 antikoerper, IL1RAPL2 antikoerper, Il18r1 antikoerper

Hintergrund: IL-18 is a proinflammatory cytokine that can synergize with IL-12 to increase IFN-γ production, NK cell cytotoxity, and Th1 responses, and involves in chronic inflammation, autoimmune diseases, and a variety of cancers. The receptor of IL-18 is a complex of two polypeptide chains, IL-18 receptor 1 (IL-18R1/IL-18Ra/CD218a) and IL-18 receptor accessory protein (IL-18Rap/IL-18 receptor ß/CD218b). Both chain are essential for IL-18 signal transduction. IL-18R1 is a glycosylated membrane protein of 60-100 kDa expressed on variety of cells containing Th1 cells, NK cells, renal epithelial cells and prostate cancer cells. It is a member of IL-1 receptor family and works as ligand binding chain of IL-18R complex.Synonyms: CD218 antigen-like family member A, CDw218a, IL-18 receptor 1, IL-1Rrp, IL1 receptor-related protein, IL1RRP, Interleukin-18 receptor 1

Gen-ID: 8809

NCBI Accession: NP_003846

UniProt: Q13478