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CD52 Antikörper

CD52 Reaktivität: Maus FACS, IP Wirt: Ratte Monoclonal BTG-2G unconjugated
Produktnummer ABIN1449230
  • Target Alle CD52 Antikörper anzeigen
    CD52
    Reaktivität
    • 62
    • 11
    • 7
    • 5
    • 4
    • 1
    Maus
    Wirt
    • 25
    • 19
    • 19
    • 1
    • 1
    Ratte
    Klonalität
    • 48
    • 11
    • 3
    Monoklonal
    Konjugat
    • 32
    • 9
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD52 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 20
    • 19
    • 16
    • 14
    • 13
    • 12
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Spezifität
    This antibody reacts with mouse CAMPATH-1/CD52.
    Aufreinigung
    Protein G agarose
    Immunogen
    Mouse IL-2R alpha-TGM splenocyte
    Klon
    BTG-2G
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD52 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Upon receipt, store (in aliqouts) at -20 °C.
  • Target
    CD52
    Andere Bezeichnung
    CD52 / CAMPATH-1 (CD52 Produkte)
    Synonyme
    CD52 antikoerper, AI463198 antikoerper, B7 antikoerper, B7-Ag antikoerper, CAMPATH-1 antikoerper, CLS1 antikoerper, MB7 antikoerper, CDW52 antikoerper, CE5 antikoerper, CD52 molecule antikoerper, CD52 antigen antikoerper, CD52 antikoerper, Cd52 antikoerper
    Hintergrund
    CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. The function of CD52 is unknown. However, CD52 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
    Gen-ID
    23833
    NCBI Accession
    NP_038734
    UniProt
    Q64389
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