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MIS18 Binding Protein 1 (MIS18BP1) Antikörper (Cy5.5)

MIS18BP1 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal Cy5.5
Produktnummer ABIN1421533
  • Target Alle MIS18 Binding Protein 1 (MIS18BP1) Antikörper anzeigen
    MIS18 Binding Protein 1 (MIS18BP1)
    Reaktivität
    • 18
    • 14
    • 14
    • 1
    Human, Maus, Ratte
    Wirt
    • 16
    • 2
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cy5.5
    Applikation
    • 18
    • 12
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KNL2/C14orf106
    Isotyp
    IgG
    Top Product
    Discover our top product MIS18BP1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MIS18 Binding Protein 1 (MIS18BP1)
    Andere Bezeichnung
    C14orf106 (MIS18BP1 Produkte)
    Synonyme
    C14orf106 antikoerper, HSA242977 antikoerper, KNL2 antikoerper, M18BP1 antikoerper, 6720403H11 antikoerper, C79407 antikoerper, Knl2 antikoerper, mKIAA1903 antikoerper, MIS18 binding protein 1 antikoerper, MIS18BP1 antikoerper, Mis18bp1 antikoerper
    Hintergrund

    Synonyms: Chromosome 14 open reading frame 106, HsKNL-2, KIAA1903, Kinetochore-associated protein KNL-2 homolog, M18BP1, Mis18-binding protein 1, MIS18BP1, P243, Putative protein p243 which interacts with transcription factor Sp1, Uncharacterized potential DNA binding protein C14orf106, M18BP_HUMAN.

    Background: C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms.Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5 % of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14,19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization.

    Pathways
    Chromatin Binding
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