KIR5.1 Antikörper (pSer416) (Cy7)

Produktnummer ABIN1413516

Der Cy7-konjugierte Kaninchen Polyklonal anti-KIR5.1 Antikörper (ABIN1413516) detektiert spezifisch KIR5.1 in IF (cc) und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KIR5.1 Antikörper (pSer416) (Cy7) (ABIN1413516)

Target: KIR5.1 (KCNJ16) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 16 (KCNJ16))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIR5.1 Antikörper ist konjugiert mit Cy7

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-KIR5.1 Antikörper (Cy7)

Bindungsspezifität: pSer416

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human KIR5.1 around the phosphorylation site of Ser416

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KIR5.1

Target: KIR5.1 (KCNJ16) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 16 (KCNJ16))

Andere Bezeichnung: KIR5.1

Hintergrund:

Synonyms: p-KIR5.1 phospho S416, 6430410F18Rik, AI132396, BIR9, Inward rectier K channel Kir5.1, Inward rectier K+ channel Kir5.1, Inward rectier potassium channel 16, IRK16, IRKG, KCNJ16, MGC33717, Potassium channel inwardly rectying subfamily J member 16, Potassium inwardly rectying channel subfamily J member 16, RP23-218O16.1, IRK16_HUMAN.

Background: The KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down?s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.