KCNA3 Antikörper (pTyr135) (Cy3)

Produktnummer ABIN1413459

Der Cy3-konjugierte Kaninchen Polyklonal anti-KCNA3 Antikörper (ABIN1413459) detektiert spezifisch KCNA3 in IF (cc) und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KCNA3 Antikörper (pTyr135) (Cy3) (ABIN1413459)

Target: KCNA3 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNA3 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-KCNA3 Antikörper (Cy3)

Bindungsspezifität: pTyr135

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human KCNA3 around the phosphorylation site of Tyr135

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KCNA3

Target: KCNA3 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3))

Andere Bezeichnung: KCNA3

Hintergrund:

Synonyms: KCNA3 phospho Y135, p-KCNA3 phospho Y135, p-KV1.3 phospho Y135, Potassium Channel Kv1.3, HGK 5, HGK5, HLK 3, HLK3, HPCN 3, HPCN3, HuKIII, KCNA 3, KCNA3, KV1.3, MK 3, MK3, PCN 3, PCN3, Potassium channel 3, Potassium voltage gated channel shaker related subfamily member 3, Potassium voltage gated channel subfamily A member 3, Type n potassium channel, Voltage gated potassium channel subunit Kv1.3, KCNA3_HUMAN.

Background: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008].