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NUMBL Antikörper (AA 75-120) (Cy5.5)

NUMBL Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5.5
Produktnummer ABIN1412309
  • Target Alle NUMBL Antikörper anzeigen
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    Bindungsspezifität
    • 14
    • 9
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    AA 75-120
    Reaktivität
    • 46
    • 9
    • 9
    • 1
    Human
    Wirt
    • 44
    • 1
    • 1
    Kaninchen
    Klonalität
    • 45
    • 1
    Polyklonal
    Konjugat
    • 12
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser NUMBL Antikörper ist konjugiert mit Cy5.5
    Applikation
    • 31
    • 22
    • 16
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NUMBL
    Isotyp
    IgG
    Top Product
    Discover our top product NUMBL Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    Andere Bezeichnung
    NUMBL (NUMBL Produkte)
    Synonyme
    nbl antikoerper, numb antikoerper, cag3a antikoerper, ctg3a antikoerper, numbr antikoerper, numb-r antikoerper, tnrc23 antikoerper, numblike antikoerper, CAG3A antikoerper, CTG3a antikoerper, NBL antikoerper, NUMB-R antikoerper, NUMBLIKE antikoerper, NUMBR antikoerper, TNRC23 antikoerper, NUMB like, endocytic adaptor protein antikoerper, numb homolog-like L homeolog antikoerper, NUMB-like, endocytic adaptor protein antikoerper, numb-like antikoerper, NUMBL antikoerper, numbl.L antikoerper, Numbl antikoerper
    Hintergrund

    Synonyms: CAG 3A, CAG3A, CTG 3a, CTG3a, NBL, NUMB Drosophilia Homolog Like, Numb homolog Drosophila like, Numb homolog like, Numb like protein, NUMB R, Numb-like protein, Numb-R, Numb-related protein, NUMBL, NUMBL_HUMAN, NUMBR, TNRC 23, TNRC23.

    Background: In Drosophila, neuronal cell fate decisions are directed by NUMB, a signaling adapter protein with two protein-protein interaction domains, namely a phosphotyrosine-binding domain and a proline-rich SH3-binding region (PRR). The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, including Eps15, LNX1 and Notch 1. NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate. Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1. In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.

    Pathways
    Cell-Cell Junction Organization
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