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SPOCK1 Antikörper (AA 51-150) (HRP)

SPOCK1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1412258
  • Target Alle SPOCK1 Antikörper anzeigen
    SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
    Bindungsspezifität
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 51-150
    Reaktivität
    • 25
    • 14
    • 12
    Human
    Wirt
    • 23
    • 2
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPOCK1 Antikörper ist konjugiert mit HRP
    Applikation
    • 21
    • 10
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Sheep,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SPOCK1/Testican 1
    Isotyp
    IgG
    Top Product
    Discover our top product SPOCK1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
    Andere Bezeichnung
    SPOCK1/Testican 1 (SPOCK1 Produkte)
    Synonyme
    SPOCK antikoerper, TESTICAN antikoerper, TIC1 antikoerper, Spock antikoerper, Ticn1 antikoerper, testican antikoerper, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 antikoerper, sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 antikoerper, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 antikoerper, SPOCK1 antikoerper, Spock1 antikoerper
    Hintergrund

    Synonyms: Sparc/osteonectin, cwcv and kazal like domains proteoglycan 1, SPOCK, Testican 1, Testican1, Testican-1, TIC1, TICN1, TICN1_HUMAN.

    Background: The Testican family, also designated the BM-40/SPARC/osteonectin family, is composed of highly conserved, extracellular, calcium-binding, sulfate proteoglycans. Expression of Testicans is detected in a variety of tissues, but is most abundant in brain. Family members include Testican-1, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, designated N-Tes. Most Testicans inhibit MT-MMPs, thereby inhibiting the activity of pro-MMP-2. Testican-1 is specifically expressed in the thalamus of the brain, and is upregulated in activated astroglial cells of the cerebrum where it mediates neuronal attachment and matrix metalloproteinase activation. After a neural injury, such as a cerebral stroke, Testican-1 expression is upregulated in astrocyte cells in order to inhibit the ability of the protein Neuro-2a to form neurite extensions. Testican-1 is also a component of joint and of the growth plate cartilage that may participate in the regulation of matrix turnover.

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