SPOCK1 Antikörper (Cy7)

Produktnummer ABIN1412256

Produktdetails anti-SPOCK1 Antikörper (Cy7)

Target: SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPOCK1 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Sheep,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPOCK1/Testican 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SPOCK1

Target: SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))

Andere Bezeichnung: Spock1/Testican 1 (SPOCK1 Produkte)

Synonyme: SPOCK antikoerper, TESTICAN antikoerper, TIC1 antikoerper, Spock antikoerper, Ticn1 antikoerper, testican antikoerper, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 antikoerper, sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 antikoerper, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 antikoerper, SPOCK1 antikoerper, Spock1 antikoerper

Hintergrund:

Synonyms: Sparc/osteonectin, cwcv and kazal like domains proteoglycan 1, SPOCK, Testican 1, Testican1, Testican-1, TIC1, TICN1, TICN1_HUMAN.

Background: The Testican family, also designated the BM-40/SPARC/osteonectin family, is composed of highly conserved, extracellular, calcium-binding, sulfate proteoglycans. Expression of Testicans is detected in a variety of tissues, but is most abundant in brain. Family members include Testican-1, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, designated N-Tes. Most Testicans inhibit MT-MMPs, thereby inhibiting the activity of pro-MMP-2. Testican-1 is specifically expressed in the thalamus of the brain, and is upregulated in activated astroglial cells of the cerebrum where it mediates neuronal attachment and matrix metalloproteinase activation. After a neural injury, such as a cerebral stroke, Testican-1 expression is upregulated in astrocyte cells in order to inhibit the ability of the protein Neuro-2a to form neurite extensions. Testican-1 is also a component of joint and of the growth plate cartilage that may participate in the regulation of matrix turnover.