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NAT8B Antikörper (AA 221-227) (HRP)

NAT8B Reaktivität: Human WB, ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1410080
  • Target Alle NAT8B Antikörper anzeigen
    NAT8B (N-Acetyltransferase 8B (GCN5-Related, Putative, Gene/pseudogene) (NAT8B))
    Bindungsspezifität
    • 14
    • 1
    • 1
    • 1
    • 1
    AA 221-227
    Reaktivität
    • 20
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 19
    • 1
    Kaninchen
    Klonalität
    • 19
    • 1
    Polyklonal
    Konjugat
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NAT8B Antikörper ist konjugiert mit HRP
    Applikation
    • 19
    • 13
    • 13
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NAT8B
    Isotyp
    IgG
    Top Product
    Discover our top product NAT8B Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    NAT8B (N-Acetyltransferase 8B (GCN5-Related, Putative, Gene/pseudogene) (NAT8B))
    Andere Bezeichnung
    NAT8B (NAT8B Produkte)
    Synonyme
    EG434057 antikoerper, Cml1 antikoerper, Cml6 antikoerper, Nat8 antikoerper, RGD621605 antikoerper, CML2 antikoerper, Hcml2 antikoerper, NAT8BP antikoerper, N-acetyltransferase 8B antikoerper, N-acetyltransferase 8B, pseudogene antikoerper, N-acetyltransferase 8B (putative, gene/pseudogene) antikoerper, NAT8B antikoerper, Nat8b-ps antikoerper, Nat8b antikoerper
    Hintergrund

    Synonyms: Camello like protein 2, Camello-like protein 2, CML2, Hcml2, N acetyltransferase 8B, NAT8B, NAT8B_HUMAN, NAT8BP, Probable N acetyltransferase 8B, Probable N-acetyltransferase 8B.

    Background: Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-8B (N-acetyltransferase 8B), also known as CML2 (camello-like protein 2), is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation. A member of the camello family, NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13.2. The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, which leads to a stop codon and subsequently, a non-functional protein that is truncated in length. Similarly, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, as it causes the N-acetyltransferase to become disrupted. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.

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