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RPRD1B Antikörper (Alexa Fluor 350)

RPRD1B Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1405695
  • Target Alle RPRD1B Antikörper anzeigen
    RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
    Reaktivität
    • 44
    • 20
    • 19
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 41
    • 3
    Kaninchen
    Klonalität
    • 41
    • 3
    Polyklonal
    Konjugat
    • 17
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RPRD1B Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 40
    • 18
    • 14
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CREPT
    Isotyp
    IgG
    Top Product
    Discover our top product RPRD1B Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
    Andere Bezeichnung
    CREPT (RPRD1B Produkte)
    Synonyme
    fb23h08 antikoerper, zgc:55687 antikoerper, wu:fb23h08 antikoerper, rprd1ba antikoerper, MGC130705 antikoerper, C13H20ORF77 antikoerper, C20orf77 antikoerper, CREPT antikoerper, NET60 antikoerper, dJ1057B20.2 antikoerper, 2610304G08Rik antikoerper, 2810446G03Rik antikoerper, Crept antikoerper, RGD1304782 antikoerper, regulation of nuclear pre-mRNA domain containing 1B antikoerper, regulation of nuclear pre-mRNA domain containing 1B L homeolog antikoerper, rprd1b antikoerper, rprd1b.L antikoerper, RPRD1B antikoerper, Rprd1b antikoerper
    Hintergrund

    Synonyms: C20orf77, Cell cycle related and expression elevated protein in tumor, Chromosome 20 open reading frame 77, CREPT, dJ1057B20.2, DKFZp434P0735, FLJ44520, Hypothetical protein LOC58490, Uncharacterized protein C20orf77, RPR1B_HUMAN.

    Background: Interacts with phosphorylated C-terminal heptapeptiderepeat domain (CTD) of the largest RNA polymerase II subunitPOLR2A, and participates in dephosphorylation of the CTD.Transcriptional regulator which enhances expression of CCND1.Promotes binding of RNA polymerase II to the CCDN1 promoter and tothe termination region before the poly-A site but decreases itsbinding after the poly-A site. Prevents RNA polymerase II fromreading through the 3' end termination site and may allow it to berecruited back to the promoter through promotion of the formationof a chromatin loop. Also enhances the transcription of a number ofother cell cycle-related genes including CDK2, CDK4, CDK6 andcyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.

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