BAALC Antikörper (Alexa Fluor 488)

Produktnummer ABIN1405018

Produktdetails anti-BAALC Antikörper (Alexa Fluor 488)

Target: BAALC (Brain and Acute Leukemia, Cytoplasmic (BAALC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAALC Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BAALC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BAALC

Target: BAALC (Brain and Acute Leukemia, Cytoplasmic (BAALC))

Andere Bezeichnung: BAALC (BAALC Produkte)

Synonyme: si:zc215i13.3 antikoerper, si:ch211-215i13.3 antikoerper, BAALC antikoerper, 2810457D07Rik antikoerper, BAALC, MAP3K1 and KLF4 binding antikoerper, brain and acute leukemia, cytoplasmic antikoerper, BAALC antikoerper, baalc antikoerper, Baalc antikoerper

Hintergrund:

Synonyms: BAALC, BAALC_HUMAN, Brain and acute leukemia cytoplasmic, Brain and acute leukemia cytoplasmic protein, brain and acute leukemia, cytoplasmic, FLJ12015.

Background: BAALC is a 180 amino acid protein that localizes to both the membrane and the cytoplasm and exists as multiple alternatively spliced isoforms. Expressed by hematopoetic and neural cells, BAALC interacts with CaMKII and is thought to play a role in synaptic function at postsynaptic lipid rafts. BAALC may be overexpressed in acute myeloid leukemia (AML), suggesting a role in tumorigenesis. The gene encoding BAALC maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.

Gen-ID: 79870