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C21ORF45 Antikörper (Alexa Fluor 555)

MIS18A Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 555
Produktnummer ABIN1404377
  • Target Alle C21ORF45 (MIS18A) Antikörper anzeigen
    C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))
    Reaktivität
    • 17
    • 16
    • 15
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 17
    Kaninchen
    Klonalität
    • 17
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser C21ORF45 Antikörper ist konjugiert mit Alexa Fluor 555
    Applikation
    • 17
    • 12
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FASP1/C21orf45
    Isotyp
    IgG
    Top Product
    Discover our top product MIS18A Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))
    Andere Bezeichnung
    FASP1 (MIS18A Produkte)
    Synonyme
    B28 antikoerper, C21orf45 antikoerper, C21orf46 antikoerper, FASP1 antikoerper, MIS18alpha antikoerper, hMis18alpha antikoerper, 2610039C10Rik antikoerper, 2810018N07Rik antikoerper, RGD1310778 antikoerper, MIS18 kinetochore protein A antikoerper, MIS18A antikoerper, Mis18a antikoerper
    Hintergrund

    Synonyms: B28, C21orf46, FASP1, hMis18alpha, MaFF interacting protein, MAFIP, MIS18A, Protein Mis18 alpha, MS18A_HUMAN.

    Background: Mapping to chromosome 21, the FASP1 gene (FAPP1-associated protein 1) encodes a 233 amino acid protein that is homologous to the fission yeast protein Mis18. In yeast, Mis18 is localized to the centrosome and forms a complex with Mis16 to maintain the deacetylated state of histones specifically in the central core of centromeres. FASP1, also known as Protein Mis18-alpha and C21orf45, is required for the recruitment of CENP-A to centrosomes and is thereby essential for normal chromosome segregation during mitosis. With expression in testis, FASP1 exists as a homodimer, a heterodimer with MIS18B or is present in a complex containing other Mis18 family members. FASP1 has been shown to bind to pp5644 in Hela cells, where overexpression of pp5644 leads to inhibited growth and colony formation.

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