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VGLL4 Antikörper (AA 220-270) (Biotin)

VGLL4 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1401331
  • Target Alle VGLL4 Antikörper anzeigen
    VGLL4 (Vestigial Like 4 (VGLL4))
    Bindungsspezifität
    • 14
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 220-270
    Reaktivität
    • 31
    • 16
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 31
    • 1
    Kaninchen
    Klonalität
    • 32
    Polyklonal
    Konjugat
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VGLL4 Antikörper ist konjugiert mit Biotin
    Applikation
    • 27
    • 13
    • 11
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human VGLL4
    Isotyp
    IgG
    Top Product
    Discover our top product VGLL4 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    VGLL4 (Vestigial Like 4 (VGLL4))
    Andere Bezeichnung
    VGLL4 (VGLL4 Produkte)
    Synonyme
    DKFZp459C0333 antikoerper, VGL-4 antikoerper, BC048841 antikoerper, vestigial-like family member 4 antikoerper, vestigial like family member 4 antikoerper, Vgll4 antikoerper, VGLL4 antikoerper
    Hintergrund

    Synonyms: Transcription cofactor vestigial like protein 4, Vestigial like protein 4, VGL 4, VGLL4, VGLL4_HUMAN.

    Background: The transcriptional enhancer factor-1 (TEF-1) family of transcription factors regulate tissue-specific gene expression in muscle and placenta. The mechanism whereby TEF-1 confers tissue specificity depends largely on the interaction of TEF-1 with tissue-specific cofactors. Transcription cofactor Vgl-4 (vestigial-like protein 4) is a 290 amino acid nuclear protein that interacts with TEF-1 and MEF-2. Vgl-4 is the only member of the vestigial-like family that is expressed in heart. Overexpression of Vgl-4 in cardiac myocytes interferes with basal expression and ?-adrenergic receptor-dependent activation of a TEF-1 dependent skeletal ?actin promoter. This suggests that Vgl-4 counteracts ?-adrenergic activation of gene expression in cardiomyocytes. There are two isoforms of Vgl-4 that are produced as a result of alternative splicing events.

    Gen-ID
    9686
    UniProt
    Q14135
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