ATAD2 Antikörper (AA 1025-1063) (Biotin)

Produktnummer ABIN1400899

Produktdetails anti-ATAD2 Antikörper (Biotin)

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Bindungsspezifität: AA 1025-1063

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATAD2 Antikörper ist konjugiert mit Biotin

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATAD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ATAD2

Target: ATAD2 (ATPase Family, AAA Domain Containing 2 (ATAD2))

Andere Bezeichnung: ATAD2 (ATAD2 Produkte)

Synonyme: ANCCA antikoerper, PRO2000 antikoerper, 2610509G12Rik antikoerper, ATPase family, AAA domain containing 2 antikoerper, Atad2 antikoerper, ATAD2 antikoerper

Hintergrund:

Synonyms: ANCCA, CT137, PRO2000, ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated protein, ATAD2, L16

Background: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.

Gen-ID: 29028

UniProt: Q6PL18