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HEXDC Antikörper (AA 1-100) (Alexa Fluor 488)

HEXDC Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 488
Produktnummer ABIN1398970
  • Target Alle HEXDC Antikörper anzeigen
    HEXDC (Hexosaminidase D (HEXDC))
    Bindungsspezifität
    • 14
    • 2
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 19
    • 1
    • 1
    Human
    Wirt
    • 17
    • 2
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HEXDC Antikörper ist konjugiert mit Alexa Fluor 488
    Applikation
    • 19
    • 12
    • 12
    • 3
    • 3
    • 3
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HEXDC
    Isotyp
    IgG
    Top Product
    Discover our top product HEXDC Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HEXDC (Hexosaminidase D (HEXDC))
    Andere Bezeichnung
    HEXDC (HEXDC Produkte)
    Synonyme
    BC069960 antikoerper, fj33c04 antikoerper, wu:fj33c04 antikoerper, zgc:152869 antikoerper, hexdc antikoerper, hexosaminidase D antikoerper, hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing antikoerper, hexosaminidase D L homeolog antikoerper, HEXDC antikoerper, Hexdc antikoerper, hexdc antikoerper, hexdc.L antikoerper
    Hintergrund

    Synonyms: Beta hexosaminidase D, Beta N acetylhexosaminidase, FLJ23825, Hexosaminidase glycosyl hydrolase family 20 catalytic domain containing, hexosaminidase glycosyl hydrolase family 20, catalytic domain, Hexosaminidase D, Hexosaminidase domain containing protein, N acetyl beta galactosaminidase, HEXDC_HUMAN.

    Background: HEXDC, also known as hexosaminidase D, beta-hexosaminidase D, N-acetyl-beta-galactosaminidase, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family. Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides. The gene encoding HEXDC maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    Gen-ID
    284004
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