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LGI4 Antikörper (AA 101-200) (Alexa Fluor 350)

LGI4 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1398309
  • Target Alle LGI4 Antikörper anzeigen
    LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
    Bindungsspezifität
    • 14
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reaktivität
    • 27
    • 10
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 27
    • 2
    Kaninchen
    Klonalität
    • 27
    • 2
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LGI4 Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 24
    • 12
    • 12
    • 10
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human LGI4
    Isotyp
    IgG
    Top Product
    Discover our top product LGI4 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    LGI4 (Leucine-Rich Repeat LGI Family, Member 4 (LGI4))
    Andere Bezeichnung
    LGI4 (LGI4 Produkte)
    Synonyme
    Lgil3 antikoerper, clp antikoerper, LGIL3 antikoerper, leucine rich repeat LGI family member 4 antikoerper, leucine-rich repeat LGI family, member 4 antikoerper, LGI4 antikoerper, Lgi4 antikoerper
    Hintergrund

    Synonyms: Leucine rich glioma inactivated gene 4, Leucine rich glioma inactivated protein 4, leucine-rich repeat LGI family member 4, Leucine rich repeat LGI family member 4, LGI1 like protein 3, LGI4, Lgi4 protein, Lgil3, LGI4_HUMAN.

    Background: LGI4, also known as leucine-rich glioma-inactivated protein 4, is a 537 amino acid secreted glycosylated protein that is widely expressed, with highest levels found within the nervous system. Interestingly, siRNA knockdown studies of LGI4 expression in Schwann cells have been shown to result in the inhibition of myelination, thus suggesting that LGI4 is an essential component of myelin formation and axon segregation. LGI4 shares significant homology with its other family members, LGI1, LGI2 and LGI3. Significantly, mutations in the gene encoding LGI1 have been linked to human temporal lobe epilepsy and, given the sequence similarity of LGI4, it is likely that it also may be implicated in the pathology of seizures. LGI4 is localized subcellularly to the Golgi, ER and vesicles. There are two isoforms of LGI4 that are produced as a result of alternative splicing events.

    Gen-ID
    163175
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