BAZ1A Antikörper (AA 1401-1556) (Alexa Fluor 488)

Produktnummer ABIN1397508

Produktdetails anti-BAZ1A Antikörper (Alexa Fluor 488)

Target: BAZ1A (Bromodomain Adjacent To Zinc Finger Domain, 1A (BAZ1A))

Bindungsspezifität: AA 1401-1556

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAZ1A Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATP utilizing chromatin assembly and remodeling factor 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BAZ1A

Target: BAZ1A (Bromodomain Adjacent To Zinc Finger Domain, 1A (BAZ1A))

Andere Bezeichnung: ACF1 (BAZ1A Produkte)

Synonyme: ACF1 antikoerper, WALp1 antikoerper, WCRF180 antikoerper, hACF1 antikoerper, fi34e04 antikoerper, wu:fi34e04 antikoerper, acf1 antikoerper, walp1 antikoerper, wcrf180 antikoerper, BAZ1A antikoerper, Acf1 antikoerper, B930060C03 antikoerper, BC065123 antikoerper, Gtl5 antikoerper, Wcrf180 antikoerper, cbp146 antikoerper, bromodomain adjacent to zinc finger domain 1A antikoerper, bromodomain adjacent to zinc finger domain, 1A antikoerper, bromodomain adjacent to zinc finger domain 1A S homeolog antikoerper, BAZ1A antikoerper, Baz1a antikoerper, baz1a antikoerper, baz1a.S antikoerper

Hintergrund:

Synonyms: BAZ1A, Acf1, ACF1, drosophila, homolog of antibody ATP dependent chromatin remodelling protein, ATP utilizing chromatin assembly and remodeling factor 1, ATP-dependent chromatin-remodeling protein, ATP-utilizing chromatin assembly and remodeling factor 1, Baz1a, BAZ1A_HUMAN, Bromodomain adjacent to zinc finger domain 1A, Bromodomain adjacent to zinc finger domain protein 1A, cbp146, CHRAC subunit ACF1, Gtl5.

Background: Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.

Gen-ID: 11177

UniProt: Q9NRL2