SCN7A Antikörper (AA 1561-1582) (Alexa Fluor 647)

Produktnummer ABIN1395318

Produktdetails anti-SCN7A Antikörper (Alexa Fluor 647)

Target: SCN7A (Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))

Bindungsspezifität: AA 1561-1582

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN7A Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SCN7A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SCN7A

Target: SCN7A (Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))

Andere Bezeichnung: SCN7A (SCN7A Produkte)

Synonyme: 1110034K09Rik antikoerper, AI642000 antikoerper, NaG antikoerper, Nav2 antikoerper, Nav2.3 antikoerper, Nax antikoerper, Scn6a antikoerper, Na-G antikoerper, Nav2.1 antikoerper, Nav2.2 antikoerper, SCN6A antikoerper, sodium channel, voltage-gated, type VII, alpha antikoerper, sodium voltage-gated channel alpha subunit 7 antikoerper, Scn7a antikoerper, SCN7A antikoerper

Hintergrund:

Synonyms: Putative voltage gated sodium channel subunit alpha Nax, SCN 6A, SCN 7A, SCN6A, Sodium channel protein cardiac and skeletal muscle subunit alpha, Sodium channel protein type 7 subunit alpha, Sodium channel protein type VII subunit alpha, Sodium channel voltage gated type VI alpha polypeptide, Sodium channel voltage gated type VII alpha, Sodium channel voltage gated type VII alpha polypeptide, Voltage dependent sodium channel alpha subunit, SCN7A_HUMAN.

Background: Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarize the cell. The three glycoproteins that comprise the voltage-gated sodium channel proteins include a pore-forming Beta subunit, a noncovalently associated Beta 1 subunit and a disulfide-linked Beta 2 subunit. Na+ CP type VII Alpha (Sodium channel protein type 7 subunit alpha), also known as SCN6A, Sodium channel protein cardiac and skeletal muscle subunit alpha and putative voltage-gated sodium channel subunit alpha Nax, is a 1682 amino acid multi-pass membrane protein that belongs to the sodium channel family. Primarily expressed in uterus and heart, Na+ CP type VII Alpha may function in the regulation of salt intake behavior and central sensing of body-fluid sodium levels.

Gen-ID: 6332

UniProt: Q01118