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Chromosome 12 Open Reading Frame 52 (C12orf52) (AA 51-150) Antikörper (Alexa Fluor 350)

C12orf52 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1394241
  • Target Alle Chromosome 12 Open Reading Frame 52 (C12orf52) Antikörper anzeigen
    Chromosome 12 Open Reading Frame 52 (C12orf52)
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 7
    AA 51-150
    Reaktivität
    Human
    Wirt
    • 29
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Alexa Fluor 350
    Applikation
    • 15
    • 15
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Cow,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RITA/C12orf52
    Isotyp
    IgG
    Top Product
    Discover our top product C12orf52 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Chromosome 12 Open Reading Frame 52 (C12orf52)
    Andere Bezeichnung
    RITA/C12orf52 (C12orf52 Produkte)
    Synonyme
    RITA antikoerper, C12orf52 antikoerper, AI853657 antikoerper, C86297 antikoerper, Rita antikoerper, RBPJ interacting and tubulin associated 1 antikoerper, RBPJ interacting and tubulin associated 1 L homeolog antikoerper, RITA1 antikoerper, rita1.L antikoerper, Rita1 antikoerper
    Hintergrund

    Synonyms: C12orf52, Chromosome 12 open reading frame 52, RBPJ-interacting and tubulin-associated protein, RITA, RITA_HUMAN.

    Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf52 gene product has been provisionally designated C12orf52 pending further characterization.

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