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NPDC1 Antikörper (AA 75-180) (Biotin)

NPDC1 Reaktivität: Maus WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1394065
  • Target Alle NPDC1 Antikörper anzeigen
    NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
    Bindungsspezifität
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 75-180
    Reaktivität
    • 29
    • 25
    • 8
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 37
    • 1
    • 1
    Kaninchen
    Klonalität
    • 38
    • 1
    Polyklonal
    Konjugat
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NPDC1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 28
    • 13
    • 13
    • 10
    • 5
    • 4
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NPDC1
    Isotyp
    IgG
    Top Product
    Discover our top product NPDC1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))
    Andere Bezeichnung
    NPDC1 (NPDC1 Produkte)
    Synonyme
    AI314472 antikoerper, NPDC-1 antikoerper, CAB antikoerper, CAB- antikoerper, CAB-1 antikoerper, CAB1 antikoerper, neural proliferation, differentiation and control, 1, gene 1 L homeolog antikoerper, neural proliferation, differentiation and control 1 antikoerper, neural proliferation, differentiation and control, 1 antikoerper, npdc1.1.L antikoerper, Npdc1 antikoerper, NPDC1 antikoerper
    Hintergrund

    Synonyms: AI314472, CAB1, Neural proliferation dferentiation and control protein 1, NPDC-1, NPDC1, NPDC1_HUMAN.

    Background: NPDC-1 (Neural Proliferation Differentiation and Control-1) is expressed in neurons once they have stopped dividing and begun to differentiate. NPDC-1 is transported from the Golgi apparatus via vesicles before becoming internalized by endosomes at the cell membrane. NPDC-1 interacts with Cdk2, D-type cyclins, and the transcription factor E2F1. This interaction can lead to an increased replication time, and might have implications in final neural differentiation and apoptosis. NPDC-1 has been shown to colocalize with synaptic vesicle proteins: synaptophysin, synaptobrevin 2, and Rab3 GEP (Rab3 GTP/GDP exchange protein). One function of NPDC-1 is to regulate retinoic acid-mediated events by directly interacting with retinoid receptors. The amino acid sequence of NPDC-1 is highly conserved between mouse, rat, and human.

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