ABCB9 Antikörper (AA 321-420) (Alexa Fluor 647)

Produktnummer ABIN1394034

Produktdetails anti-ABCB9 Antikörper (Alexa Fluor 647)

Target: ABCB9 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 9 (ABCB9))

Bindungsspezifität: AA 321-420

Reaktivität: Maus, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB9 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Maus, Schwein, Ratte

Homologie: Human,Dog,Cow,Sheep,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABCB9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ABCB9

Target: ABCB9 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 9 (ABCB9))

Andere Bezeichnung: ABCB9 (ABCB9 Produkte)

Synonyme: ABCB9 antikoerper, si:dkey-21k4.3 antikoerper, EST122234 antikoerper, TAPL antikoerper, mKIAA1520 antikoerper, Tapl antikoerper, ATP binding cassette subfamily B member 9 antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 9 antikoerper, ABCB9 antikoerper, abcb9 antikoerper, Abcb9 antikoerper

Hintergrund:

Synonyms: ABC transporter 9 protein, ABCB 9, ATP binding cassette sub family B MDR/TAP member 9, ATP binding cassette sub family B member 9 precursor, ATP binding cassette transporter 9, EST122234, ABCB9, KIAA1520, TAP like protein, TAPL, ABCB9_HUMAN.

Background: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. As the largest family of transmembrane proteins, ABC genes comprise several subfamilies (ABC1, ABCA, ABCE, ABCF, MDR/TAP, MRP, ALD, OABP, GCN20 and White (also known as ABCG)). In bacteria, ABC transporters are used to import compunds that cannot be obtained by diffusion. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process or outside the cell for transport to other organs, or for secretion from the body. ABCB9 (also designated Transporter associated with antigen processing (TAP)-like or TAPL) forms a homodimer, which is localized in lysosomes. It functions as an ATP-dependent peptide transporter that shows a broad peptide specificity ranging from 6-mer up to 59-mer peptides. ABCB9 transports these peptides with low affinity but high efficiency.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process