CTRP5 Antikörper (AA 191-243) (Alexa Fluor 555)

Produktnummer ABIN1392923

Produktdetails anti-CTRP5 Antikörper (Alexa Fluor 555)

Target: CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))

Bindungsspezifität: AA 191-243

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTRP5 Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CTRP5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CTRP5

Target: CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))

Andere Bezeichnung: CTRP5 (C1QTNF5 Produkte)

Synonyme: C1QTNF5 antikoerper, wu:fb02c10 antikoerper, wu:fb02f05 antikoerper, zgc:112378 antikoerper, CTRP5 antikoerper, Ctrp5 antikoerper, C1q and tumor necrosis factor related protein 5 antikoerper, C1q and TNF related 5 antikoerper, C1QTNF5 antikoerper, c1qtnf5 antikoerper, C1qtnf5 antikoerper

Hintergrund:

Synonyms: C1q and tumor necrosis factor related protein 5, C1QTNF5, Complement C1q tumor necrosis factor related protein 5 precursor, LORD, C1QT5_HUMAN.

Background: Members of the C1q superfamily have diverse functions that are related to cell adhesion and basement membrane components. CTRP5 (Complement C1q tumor necrosis factor-related protein 5) is a 243 amino acid secreted and membrane-associated protein that contains a collagen-like domain and a C1q domain. CTRP5 is a short-chain collagen that is expressed in retinal pigment epithelium as well as brain, lung, liver and placenta. By forming an extracellular hexagonal lattice, CTRP5 facilitates the adhesion of basal retinal pigment epithelium to Bruch?s membrane, the innermost layer of the choroid. A mutation within the C1q domain of CTRP5 results in abnormal high molecular weight aggregate formation, which alters its structure and interactions. This mutation may result in the presentation of late-onset retinal degeneration (LORD), an autosomal dominant disorder that is characterized by punctate yellow-white deposits in the retinal fundus and night blindness.

Gen-ID: 114902

UniProt: Q9BXJ0