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SH3PXD2A Antikörper (AA 261-360) (Alexa Fluor 647)

SH3PXD2A Reaktivität: Ratte IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 647
Produktnummer ABIN1392498
  • Target Alle SH3PXD2A Antikörper anzeigen
    SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
    Bindungsspezifität
    • 14
    • 11
    • 9
    • 6
    • 1
    • 1
    AA 261-360
    Reaktivität
    • 30
    • 15
    • 10
    Ratte
    Wirt
    • 42
    • 1
    • 1
    Kaninchen
    Klonalität
    • 44
    Polyklonal
    Konjugat
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SH3PXD2A Antikörper ist konjugiert mit Alexa Fluor 647
    Applikation
    • 20
    • 19
    • 12
    • 12
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FISH
    Isotyp
    IgG
    Top Product
    Discover our top product SH3PXD2A Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
    Andere Bezeichnung
    FISH (SH3PXD2A Produkte)
    Synonyme
    FISH antikoerper, SH3MD1 antikoerper, TKS5 antikoerper, 2310014D11Rik antikoerper, AA589508 antikoerper, AI256723 antikoerper, AI413738 antikoerper, C230050L11 antikoerper, EG329070 antikoerper, Fish antikoerper, Gm5098 antikoerper, Sh3md1 antikoerper, TSK5 antikoerper, Tks5 antikoerper, sh3pxd2a antikoerper, si:dkey-82d4.2 antikoerper, SH3 and PX domains 2A antikoerper, SH3 and PX domains 2Aa antikoerper, SH3PXD2A antikoerper, Sh3pxd2a antikoerper, sh3pxd2aa antikoerper
    Hintergrund

    Synonyms: Adapter protein TKS5, Five SH3 domain-containing protein, SH3 and PX domain-containing protein 2A, SH3 multiple domains protein 1, Sh3md1, Sh3pxd2a, SPD2A_HUMAN, TKs5, Tyrosine kinase substrate with five SH3 domains.

    Background: Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo, catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).

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