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PKD1L3 Antikörper (AA 121-220) (Alexa Fluor 488)

PKD1L3 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 488
Produktnummer ABIN1392364
  • Target Alle PKD1L3 Antikörper anzeigen
    PKD1L3 (Polycystic Kidney Disease 1 Like 3 (PKD1L3))
    Bindungsspezifität
    • 14
    • 5
    AA 121-220
    Reaktivität
    Human
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PKD1L3 Antikörper ist konjugiert mit Alexa Fluor 488
    Applikation
    • 12
    • 12
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PKD1L3
    Isotyp
    IgG
    Top Product
    Discover our top product PKD1L3 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PKD1L3 (Polycystic Kidney Disease 1 Like 3 (PKD1L3))
    Andere Bezeichnung
    PKD1L3 (PKD1L3 Produkte)
    Synonyme
    polycystic kidney disease 1 like 3 antikoerper, polycystin 1 like 3, transient receptor potential channel interacting antikoerper, Pkd1l3 antikoerper, PKD1L3 antikoerper
    Hintergrund

    Synonyms: PC1 like 3 protein, Polycystic kidney disease 1 like 3, Polycystic kidney disease protein 1 like 3, Polycystin 1 like 3, Polycystin 1L3,PK1L3_HUMAN.

    Background: Polycystin-1L3 is a 1,732 amino acid multi-pass membrane protein that contains one PLAT domain, one GPS domain and one C-type lectin domain. Expressed at high levels in placenta and present at lower levels in lung and heart, Polycystin-1L3 is thought to function as an ion-channel regulator that may interact with Polycystin-L and play a role in heteromeric taste channels. The gene encoding Polycystin-1L3 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

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