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RAPGEF2 Antikörper (AA 501-600) (Alexa Fluor 555)

RAPGEF2 Reaktivität: Human WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 555
Produktnummer ABIN1392119
  • Target Alle RAPGEF2 Antikörper anzeigen
    RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
    Bindungsspezifität
    • 14
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 501-600
    Reaktivität
    • 29
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 27
    • 2
    Kaninchen
    Klonalität
    • 28
    • 1
    Polyklonal
    Konjugat
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RAPGEF2 Antikörper ist konjugiert mit Alexa Fluor 555
    Applikation
    • 23
    • 12
    • 12
    • 10
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RAPGEF2
    Isotyp
    IgG
    Top Product
    Discover our top product RAPGEF2 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
    Andere Bezeichnung
    RAPGEF2/PDZ-GEF1 (RAPGEF2 Produkte)
    Synonyme
    MGC83978 antikoerper, RAPGEF2 antikoerper, fa11h07 antikoerper, wu:fa11h07 antikoerper, CNrasGEF antikoerper, NRAPGEP antikoerper, PDZ-GEF1 antikoerper, PDZGEF1 antikoerper, RA-GEF antikoerper, Rap-GEP antikoerper, nRap GEP antikoerper, 5830453M24Rik antikoerper, CNRasGEF antikoerper, Pdzgef1 antikoerper, RA-GEF-1 antikoerper, mKIAA0313 antikoerper, nRapGEP antikoerper, Rap guanine nucleotide exchange factor 2 antikoerper, Rap guanine nucleotide exchange factor 2 L homeolog antikoerper, Rap guanine nucleotide exchange factor (GEF) 2 antikoerper, RAPGEF2 antikoerper, rapgef2.L antikoerper, rapgef2 antikoerper, Rapgef2 antikoerper
    Hintergrund

    Synonyms: KIAA0313, Neural RAP guanine nucleotide exchange protein, nRap GEP, NRAPGEP, PDZ domain containing guanine nucleotide exchange factor 1, PDZ domain-containing guanine nucleotide exchange factor 1, PDZ GEF1, PDZ-GEF1, PDZGEF1, RA GEF, RA-GEF, Rap guanine nucleotide exchange factor 2, Rapgef2, RPGF2_HUMAN.

    Background: PDZ-GEF1 is a 1,499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, Rap 1B and Rap 2B GTPases. Expressed at highest levels in brain, PDZ-GEF1 is found at low levels in placenta, heart, lung and kidney, and undergoes post-translational phosphorylation following DNA damage. PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, a Ras-associating domain, one PDZ (DHR) domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain. The gene encoding PDZ-GEF1 maps to human chromosome 4q32.1.

    Pathways
    Neurotrophin Signalübertragung
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