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TOR1B Antikörper (AA 281-336) (Alexa Fluor 647)

TOR1B Reaktivität: Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 647
Produktnummer ABIN1391580
  • Target Alle TOR1B Antikörper anzeigen
    TOR1B (Torsin Family 1, Member B (Torsin B) (TOR1B))
    Bindungsspezifität
    • 14
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    AA 281-336
    Reaktivität
    • 32
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 14
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TOR1B Antikörper ist konjugiert mit Alexa Fluor 647
    Applikation
    • 47
    • 28
    • 15
    • 12
    • 12
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Torsin B
    Isotyp
    IgG
    Top Product
    Discover our top product TOR1B Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TOR1B (Torsin Family 1, Member B (Torsin B) (TOR1B))
    Abstract
    TOR1B Produkte
    Synonyme
    MGC82811 antikoerper, tor1a antikoerper, 2610016F05Rik antikoerper, DQ1 antikoerper, torsinB antikoerper, torsin family 1, member B (torsin B) L homeolog antikoerper, torsin family 1, member B (torsin B) antikoerper, torsin family 1 member B antikoerper, torsin family 1, member B antikoerper, tor1b.L antikoerper, tor1b antikoerper, TOR1B antikoerper, Tor1b antikoerper
    Hintergrund

    Synonyms: DQ1, Tor1b, Torsin 1B, TOR1B, FKSG18, Torsin family 1 member B, TOR1B_HUMAN.

    Background: TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family. Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins. Via its ability to regulate protein folding, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development. TorsinB contains two PKC (protein kinase C) phosphorylations sites, one ATP binding domain and several conserved cysteines and shares 69 % amino acid identity with TorsinA, a related family member. Defects in the gene encoding TorsinB are associated with torsion dystonia, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body.

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