GNRHR2 Antikörper (AA 81-180) (Biotin)
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- Target Alle GNRHR2 Produkte
- GNRHR2 (Gonadotropin-Releasing Hormone (Type 2) Receptor 2 (GNRHR2))
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Bindungsspezifität
- AA 81-180
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Reaktivität
- Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GNRHR2 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Schwein
- Homologie
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GNRHR2
- Isotyp
- IgG
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- GNRHR2 (Gonadotropin-Releasing Hormone (Type 2) Receptor 2 (GNRHR2))
- Andere Bezeichnung
- GNRHR2 (GNRHR2 Produkte)
- Synonyme
- gnrhr1/iii antikoerper, GnRH-II-R antikoerper, gonadotropin releasing hormone receptor 2 (pseudogene) antikoerper, gonadotropin-releasing hormone (type 2) receptor 2 antikoerper, gnrhr2 antikoerper, GNRHR2 antikoerper
- Hintergrund
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Synonyms: GnRH IIR, Putative gonadotropin-releasing hormone II receptor, gonadotropin-releasing hormone type 2 receptor 2, GnRH-II-R, Type II GnRH receptor, GNRR2_HUMAN.
Background: Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle. This hypothalamic hormone is transported to the pituitary, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Localized to the cell membrane, GnRHR2 mediates its own receptor activity via association with G proteins, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function. GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, suggesting a possible role in tumor suppression. Due to alternative splicing events, GnRHR2 is expressed as two isoforms.
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