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DYNLT1 Antikörper (AA 21-100) (Biotin)

DYNLT1 Reaktivität: Human ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1390513
  • Target Alle DYNLT1 Antikörper anzeigen
    DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))
    Bindungsspezifität
    • 14
    • 1
    • 1
    • 1
    AA 21-100
    Reaktivität
    • 19
    • 3
    • 2
    Human
    Wirt
    • 19
    Kaninchen
    Klonalität
    • 19
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DYNLT1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 13
    • 13
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TCTEL1
    Isotyp
    IgG
    Top Product
    Discover our top product DYNLT1 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))
    Andere Bezeichnung
    TCTEL1/DYNLT1 (DYNLT1 Produkte)
    Synonyme
    cw-1 antikoerper, tctel1 antikoerper, dynlt1a antikoerper, tctex-1 antikoerper, MGC85297 antikoerper, tctex1 antikoerper, Ci-LC3 antikoerper, CW-1 antikoerper, TCTEL1 antikoerper, AGS2 antikoerper, Tctex1 antikoerper, dynein light chain Tctex-type 1 L homeolog antikoerper, dynein light chain Tctex-type 1 antikoerper, dynein, light chain, Tctex-type 1 antikoerper, dynlt1.L antikoerper, DYNLT1 antikoerper, dynlt1 antikoerper, Dynlt1 antikoerper
    Hintergrund

    Synonyms: Dynein light chain Tctex-type 1, Protein CW-1, T-complex testis-specic protein 1 homolog, DYLT1_HUMAN.

    Background: Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors, the complex transports cellular cargos towards the central region of the cell. Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. Cytoplasmic Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. The carboxy terminus of Dynein is important for microtubule-dependent motility and is highly conserved, while the amino terminal regions are more variable. Tctex1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X?(SCN10A). Tctex1, also designated CW-1 or TCTEL1 is expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Several proteins regulate Dynein activity, including dynactin, LIS1 and NudEL(NudE-like).

    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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