LRFN2 Antikörper (AA 401-500) (Biotin)

Produktnummer ABIN1389193

Produktdetails anti-LRFN2 Antikörper (Biotin)

Target: LRFN2 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 2 (LRFN2))

Bindungsspezifität: AA 401-500

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRFN2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRFN2/SALM1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu LRFN2

Target: LRFN2 (Leucine Rich Repeat and Fibronectin Type III Domain Containing 2 (LRFN2))

Andere Bezeichnung: LRFN2/SALM1 (LRFN2 Produkte)

Synonyme: FIGLER2 antikoerper, KIAA1246 antikoerper, RP11-535K1.2 antikoerper, SALM1 antikoerper, 5730420O05Rik antikoerper, mKIAA1246 antikoerper, Salm1 antikoerper, leucine rich repeat and fibronectin type III domain containing 2 antikoerper, LRFN2 antikoerper, Lrfn2 antikoerper

Hintergrund:

Synonyms: leucine rich repeat and fibronectin type III domain containing 2, RP11-535K1.2, fibronectin type III, immunoglobulin and leucine rich repeat domains 2 antibody FIGLER2, Leucine-rich repeat and fibronectin type-III domain-containing protein 2, LRFN2, LRFN2_HUMAN, SALM1, Synaptic adhesion-like molecule 1.

Background: LRFN2 is a 789 amino acid single-pass type I membrane protein belonging to the LRFN family. Encoded by a gene that maps to human chromosome 6p21.2, LRFN2 is moderately expressed in brain, spleen and testis. LRFN2 contains one fibronectin type-III domain, one Ig-like (immunoglobulin-like) domain and six LRR (leucine-rich) repeats. LRFN2 promotes neurite outgrowth in hippocampal neurons, enhances cell surface expression of two NMDA receptor subunits, NMDA1 and NMDA?1, and may play a role in redistributing PSD-95 to cell periphery. LRFN2 forms heteromeric complexes with LRFN1, LRFN3, LRFN4 and LRFN5, and is capable of forming homomeric complexes, but not across cell junctions.

Pathways: Synaptic Membrane