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TANC1 Antikörper (AA 31-130) (Alexa Fluor 350)

TANC1 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1388895
  • Target Alle TANC1 Antikörper anzeigen
    TANC1 (Tetratricopeptide Repeat, Ankyrin Repeat and Coiled-Coil Containing 1 (TANC1))
    Bindungsspezifität
    • 14
    • 2
    • 1
    • 1
    AA 31-130
    Reaktivität
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 18
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TANC1 Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 12
    • 12
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TANC1
    Isotyp
    IgG
    Top Product
    Discover our top product TANC1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TANC1 (Tetratricopeptide Repeat, Ankyrin Repeat and Coiled-Coil Containing 1 (TANC1))
    Andere Bezeichnung
    TANC1 (TANC1 Produkte)
    Synonyme
    ROLSB antikoerper, TANC antikoerper, 1200003E16Rik antikoerper, Tanc antikoerper, mKIAA1728 antikoerper, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 antikoerper, TANC1 antikoerper, Tanc1 antikoerper
    Hintergrund

    Synonyms: ROLSB, Protein TANC1, Rolling pebbles homolog B, TANC, Tanc1, TANC1_HUMAN, Tetratricopeptide repeat ankyrin repeat and coiled coil containing 1, Tetratricopeptide repeat ankyrin repeat and coiled coil domain containing protein 1, TPR domain ankyrin repeat and coiled coil containing.

    Background: TANC (tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein), also known as TANC1, is a 1,861 amino acid postsynaptic cell membrane protein that contains eleven ANK repeats, three TPR repeats and belongs to the TANC family. Considered a scaffolding component in the postsynaptic density, TANC interacts with TNIK, SAPAP1, Alpha-internexin, CaMKII, NMDA 2 and GluR-1. It is also thought that TANC interacts directly with SAP 97, PSD-95 and Homer. Upon stimulation by Rap 2, MINK1 and TNIK may phosphorylate TANC. The TANC gene encodes two alternatively spliced isoforms, contains approximately 264,025 bases and maps to human chromosome 2q24.2. Making up approximately 8 % of the human genome, chromosome 2 consists of 237 million bases and encodes over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.

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