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TFAM Antikörper (AA 155-246)

TFAM Reaktivität: Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1387734
  • Target Alle TFAM Antikörper anzeigen
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    Bindungsspezifität
    • 14
    • 13
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 155-246
    Reaktivität
    • 61
    • 29
    • 25
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 89
    • 4
    Kaninchen
    Klonalität
    • 79
    • 14
    Polyklonal
    Konjugat
    • 42
    • 11
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TFAM Antikörper ist unkonjugiert
    Applikation
    • 73
    • 39
    • 28
    • 27
    • 18
    • 16
    • 15
    • 13
    • 13
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Sheep,Pig,Rabbit,Goat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MtTF1
    Isotyp
    IgG
    Top Product
    Discover our top product TFAM Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Yan, Liu, Guan, Guo: "Deferoxamine ameliorates adipocyte dysfunction by modulating iron metabolism in ob/ob mice." in: Endocrine connections, Vol. 7, Issue 4, pp. 604-616, (2018) (PubMed).

    You, Hou, Zhai, Li, Li, Zhao, Zhao: "Protective effects of PGC-1α via the mitochondrial pathway in rat brains after intracerebral hemorrhage." in: Brain research, Vol. 1646, pp. 34-43, (2016) (PubMed).

    Yan, Ji, Shi, Li, Sang: "Acute nitrogen dioxide inhalation induces mitochondrial dysfunction in rat brain." in: Environmental research, Vol. 138, pp. 416-24, (2015) (PubMed).

  • Target
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    Andere Bezeichnung
    MtTF1 (TFAM Produkte)
    Synonyme
    tcf6 antikoerper, mttf1 antikoerper, mttfa antikoerper, tcf6l1 antikoerper, tcf6l2 antikoerper, tcf6l3 antikoerper, mttfa-A antikoerper, xl-mtTFA antikoerper, MGC153358 antikoerper, zgc:153358 antikoerper, MTTF1 antikoerper, MTTFA antikoerper, TCF6 antikoerper, TCF6L1 antikoerper, TCF6L2 antikoerper, TCF6L3 antikoerper, AI661103 antikoerper, Hmgts antikoerper, mtTFA antikoerper, tsHMG antikoerper, Mttfa antikoerper, transcription factor A, mitochondrial antikoerper, transcription factor A, mitochondrial L homeolog antikoerper, TFAM antikoerper, tfam.L antikoerper, tfam antikoerper, Tfam antikoerper
    Hintergrund

    Synonyms: TCF6, MTTF1, MTTFA, TCF6L1, TCF6L2, TCF6L3, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, TCF-6, Transcription factor 6-like 2, TFAM

    Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.

    Gen-ID
    7019
    UniProt
    Q00059
    Pathways
    Chromatin Binding
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