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Geminin Antikörper (AA 110-142)

GMNN Reaktivität: Human, Maus, Ratte WB, IHC (p), IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1387623
  • Target Alle Geminin (GMNN) Antikörper anzeigen
    Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 110-142
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 47
    • 8
    Kaninchen
    Klonalität
    • 44
    • 11
    Polyklonal
    Konjugat
    • 30
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Geminin Antikörper ist unkonjugiert
    Applikation
    • 31
    • 25
    • 24
    • 13
    • 8
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Geminin
    Isotyp
    IgG
    Top Product
    Discover our top product GMNN Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
    Andere Bezeichnung
    Geminin (GMNN Produkte)
    Synonyme
    CG3183 antikoerper, Dm Geminin antikoerper, Dm geminin antikoerper, Dmel\\CG3183 antikoerper, Gem antikoerper, Geminin antikoerper, anon-WO0257455.1 antikoerper, gem antikoerper, l(2)k14019 antikoerper, v(2)k09107 antikoerper, sb:cb254 antikoerper, zgc:66217 antikoerper, GB16871 antikoerper, GMNN antikoerper, geminin antikoerper, dyak_GLEANR_833 antikoerper, DyakGE24654 antikoerper, GE24654 antikoerper, LOC100049517 antikoerper, AW546347 antikoerper, geminin, DNA replication inhibitor antikoerper, CG3183 gene product from transcript CG3183-RA antikoerper, geminin antikoerper, GE24654 gene product from transcript GE24654-RA antikoerper, GMNN antikoerper, geminin antikoerper, gmnn antikoerper, LOC410093 antikoerper, Dyak\geminin antikoerper, Gmnn antikoerper
    Hintergrund

    Synonyms: Gem, Geminin, GMNN

    Background: Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control.

    Gen-ID
    51053
    UniProt
    O75496
    Pathways
    EGFR Signaling Pathway, DNA Replication
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