BBS1 Antikörper (AA 181-270)

Produktnummer ABIN1387440

Produktdetails anti-BBS1 Antikörper

Target: BBS1 (Bardet-Biedl Syndrome 1 (BBS1))

Bindungsspezifität: AA 181-270

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BBS1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BBS1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu BBS1

Target: BBS1 (Bardet-Biedl Syndrome 1 (BBS1))

Andere Bezeichnung: BBS1 (BBS1 Produkte)

Synonyme: im:7144669 antikoerper, bbs2l2 antikoerper, BBS1 antikoerper, DKFZp468B1612 antikoerper, BBS2L2 antikoerper, AI451249 antikoerper, D19Ertd609e antikoerper, Bardet-Biedl syndrome 1 antikoerper, bardet-biedl syndrome 1 antikoerper, Bardet-Biedl syndrome 1 (human) antikoerper, BBS1 antikoerper, bbs1 antikoerper, Bbs1 antikoerper

Hintergrund:

Synonyms: AI451249, Bardet-Biedl syndrome 1, Bardet-Biedl syndrome 1 homolog, Bardet-Biedl syndrome 1 protein, BBS1, BBS1_HUMAN, BBS2-like protein 2, D19Ertd609e.

Background: The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.

Pathways: Hedgehog Signalweg