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UNC93B1 Antikörper (AA 451-550)

UNC93B1 Reaktivität: Human ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386855
  • Target Alle UNC93B1 Antikörper anzeigen
    UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
    Bindungsspezifität
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-550
    Reaktivität
    • 16
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 15
    • 1
    Kaninchen
    Klonalität
    • 16
    Polyklonal
    Konjugat
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UNC93B1 Antikörper ist unkonjugiert
    Applikation
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human UNC93B
    Isotyp
    IgG
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    UNC93B1 (Unc-93 Homolog B1 (UNC93B1))
    Andere Bezeichnung
    UNC93B (UNC93B1 Produkte)
    Synonyme
    UNC93 antikoerper, IIAE1 antikoerper, UNC93B antikoerper, Unc-93B1 antikoerper, Unc93b antikoerper, unc-93 homolog B1, TLR signaling regulator antikoerper, unc-93 homolog B1 (C. elegans) antikoerper, UNC93B1 antikoerper, Unc93b1 antikoerper
    Hintergrund

    Synonyms: IIAE1, UNC93, UNC93B, Unc-93B1, Protein unc-93 homolog B1, hUNC93B1, UNC93B1

    Background: Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.

    Gen-ID
    81622
    UniProt
    Q9H1C4
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
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