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DLGAP2 Antikörper (AA 251-360)

DLGAP2 Reaktivität: Human, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386703
  • Target Alle DLGAP2 Antikörper anzeigen
    DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))
    Bindungsspezifität
    • 14
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-360
    Reaktivität
    • 21
    • 16
    • 4
    Human, Ratte
    Wirt
    • 23
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DLGAP2 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 12
    • 12
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Ratte
    Homologie
    Mouse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SAPAP2/DLGAP2
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DLGAP2 (Discs, Large (Drosophila) Homolog-Associated Protein 2 (DLGAP2))
    Andere Bezeichnung
    SAPAP2/DLGAP2 (DLGAP2 Produkte)
    Synonyme
    PSD-95 antikoerper, DAP2 antikoerper, SAPAP2 antikoerper, 6430596N04Rik antikoerper, Sapap2 antikoerper, DLG associated protein 2 antikoerper, disks large-associated protein 2 antikoerper, discs, large (Drosophila) homolog-associated protein 2a antikoerper, discs, large (Drosophila) homolog-associated protein 2 antikoerper, DLGAP2 antikoerper, LOC463960 antikoerper, dlgap2a antikoerper, LOC100447448 antikoerper, Dlgap2 antikoerper
    Hintergrund

    Synonyms: DAP-2, DAP2, Discs large Drosophila homolog associated protein 2, Discs large homolog associated protein 2, Disks large-associated protein 2, Dlgap2, DLGP2_HUMAN, PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, SAPAP2, hide.

    Background: A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP2, also known as DAP-2 (Disks large-associated protein 2) and PSD-95/SAP90-binding protein 2, is a 1054 amino acid protein that localizes to the postsynaptic membrane of neuronal cells of the brain and kidney. SAPAP2 likely acts as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP2, DLGAP2, maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.

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