SLC6A7 Antikörper (AA 151-260)

Produktnummer ABIN1386693

Produktdetails anti-SLC6A7 Antikörper

Target: SLC6A7 (Solute Carrier Family 6 (Neurotransmitter Transporter, L-Proline), Member 7 (SLC6A7))

Bindungsspezifität: AA 151-260

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC6A7 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC6A7/PROT

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SLC6A7

Target: SLC6A7 (Solute Carrier Family 6 (Neurotransmitter Transporter, L-Proline), Member 7 (SLC6A7))

Andere Bezeichnung: SLC6A7/PROT (SLC6A7 Produkte)

Synonyme: slc6a7 antikoerper, AW455934 antikoerper, PROT antikoerper, Prot antikoerper, solute carrier family 6 member 7 antikoerper, zgc:158225 antikoerper, solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 antikoerper, SLC6A7 antikoerper, zgc:158225 antikoerper, slc6a7 antikoerper, Slc6a7 antikoerper

Hintergrund:

Synonyms: SC6A7_HUMAN, Slc6a7, Sodium-dependent proline transporter, Solute carrier family 6 member 7.

Background: The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients. PROT (Sodium-dependent proline transporter), also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain. PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals. Enriched in glutamatergic synaptic terminals, it is likely that PROT plays an important role in excitatory events of neurotransmission. PROT-mediated proline uptake is inhibited by compounds such as benztropine, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL). These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders.