Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) Antikörper

Details zu Produkt Nr. ABIN1386516, Anbieter: Anmelden zum Anzeigen
Antigen
  • APBA1
  • 6430513E09Rik
  • Lin-10
  • Mint
  • Mint1
  • Urop11
  • X11
  • X11alpha
  • D9S411E
  • LIN10
  • MINT1
  • X11A
  • X11ALPHA
  • amyloid beta precursor protein binding family A member 1
  • amyloid beta (A4) precursor protein-binding, family A, member 1b
  • ketopantoate reductase
  • 2-dehydropantoate 2-reductase
  • amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
  • amyloid beta (A4) precursor protein-binding, family A, member 1
  • amyloid beta (A4) precursor protein binding, family A, member 1
  • APBA1
  • apba1b
  • apbA1
  • apba1
  • Apba1
Reaktivität
Human, Maus, Ratte (Rattus)
73
48
41
2
2
1
1
1
1
1
1
1
1
Wirt
Kaninchen
63
17
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
57
44
17
12
9
4
3
2
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide derived from human APBA1
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Apba1 (APBA1 Antibody Abstract)
Hintergrund

The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the â^-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11å (also designated Mint 1), X11Beta (Mint 2) and X11(Mint 3).

Synonyms: Adapter protein X11 alpha, Adapter protein X11alpha, Amyloid beta A4 precursor protein-binding family A member 1, Apba1, APBA1_HUMAN, Mint 1, Mint-1, Neuron specic X11 protein, Neuron-specic X11 protein, Neuronal Munc18 1 interacting protein 1, Neuronal Munc18-1-interacting protein 1, UROP11, x11, X11alpha.

Pathways Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1) antibody (ABIN1386516) Paraformaldehyde-fixed, paraffin embedded mouse brain; Antigen retrieval by boiling i...
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