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P2RX7 Antikörper (AA 115-160)

P2RX7 Reaktivität: Human, Maus WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386314
  • Target Alle P2RX7 Antikörper anzeigen
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    Bindungsspezifität
    • 14
    • 11
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 115-160
    Reaktivität
    • 57
    • 39
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 56
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 57
    • 4
    Polyklonal
    Konjugat
    • 27
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser P2RX7 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 26
    • 22
    • 12
    • 12
    • 12
    • 10
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human P2RX7
    Isotyp
    IgG
    Top Product
    Discover our top product P2RX7 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Zhou, Tan, Mo, Gao, He, Li, Huang, Li, Guo, Guo, Wang, Yang, Zhang: "P2X7 receptor in spinal tuberculosis: Gene polymorphisms and protein levels in Chinese Han population." in: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, Vol. 57, pp. 138-144, (2017) (PubMed).

    Peng, Liu, Wei, Lv, Wang, Xiong, Wang, Altaf, Wang, He, Wang, Qu: "P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation." in: International journal of molecular medicine, Vol. 35, Issue 5, pp. 1179-88, (2015) (PubMed).

  • Target
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    Andere Bezeichnung
    P2RX7 (P2RX7 Produkte)
    Synonyme
    p2xr7 antikoerper, P2RX7 antikoerper, P2X7 antikoerper, AI467586 antikoerper, P2X(7) antikoerper, P2X7R antikoerper, p2x7 antikoerper, purinergic receptor P2X 7 antikoerper, purinergic receptor P2X, ligand-gated ion channel, 7 antikoerper, P2X purinoceptor 7 antikoerper, P2RX7 antikoerper, p2rx7 antikoerper, LOC100458463 antikoerper, P2rx7 antikoerper
    Hintergrund

    Synonyms: P2X7, P2X purinoceptor 7, ATP receptor, P2Z receptor, Purinergic receptor, P2RX7

    Background: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.

    Gen-ID
    5027
    UniProt
    Q99572
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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