PPP1R10 Antikörper (AA 151-250)

Produktnummer ABIN1386277

Produktdetails anti-PPP1R10 Antikörper

Target: PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))

Bindungsspezifität: AA 151-250

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1R10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PNUTS/PPP1R10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PPP1R10

Target: PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))

Andere Bezeichnung: PNUTS/PPP1R10 (PPP1R10 Produkte)

Synonyme: CAT53 antikoerper, FB19 antikoerper, PNUTS antikoerper, PP1R10 antikoerper, R111 antikoerper, p99 antikoerper, Fb19 antikoerper, Pnuts antikoerper, 2610025H06Rik antikoerper, Cat53 antikoerper, D17Ertd808e antikoerper, CHUNP6885 antikoerper, fe15d12 antikoerper, fk54b08 antikoerper, ppp1r10l antikoerper, wu:fe15d12 antikoerper, wu:fk54b08 antikoerper, protein phosphatase 1 regulatory subunit 10 antikoerper, protein phosphatase 1, regulatory subunit 10 antikoerper, protein phosphatase 1 regulatory subunit 10 S homeolog antikoerper, PPP1R10 antikoerper, Ppp1r10 antikoerper, ppp1r10.S antikoerper, ppp1r10 antikoerper

Hintergrund:

Synonyms: CAT 53, CAT53, FB 19, FB19, FB19 protein, MHC class I region proline rich protein CAT53, p99, Phosphatase 1 nuclear targeting subunit, Phosphatase nuclear targeting subunit, PNUTS, PP1 binding protein of 114 kDa, PP1R10, Protein phosphatase 1 regulatory inhibitor subunit 10, Protein phosphatase 1 regulatory subunit 10, Serine/threonine protein phosphatase 1 regulatory subunit 10, PP1RA_HUMAN.

Background: Eukaryotic protein phosphorylation and dephosphorylation on serine and threonine residues regulates numerous cell functions, including division, homeostasis and apoptosis. A group of proteins that play a major role in this process are the serine/threonine protein phosphatases. Protein phosphatase (PP) holoenzyme is a trimeric complex that contains a regulatory subunit, a variable subunit and a catalytic subunit. Families of PP catalytic subunits include PP1, PP2A, PP2B, PP2C, PPX and PP5. Regulatory subunits include nuclear inhibitor of PP1 (NIPP1), PP1 nuclear targeting subunit (PNUTS), PP2A-A, PP2A-B, PP2A-B56, PP2A-C, PP2B-B and PR48. PNUTS, also designated CAT53 or FB19, is encoded by the gene PPP1R10. PNUTS acts as an inhibitor for the phosphatase activity of PP1 Alpha and PP1 Gamma. It is a nuclear protein primarily detected in nucleoplasmic bodies and within nucleoli. PNUTS expression levels are highest in brain, heart, lung, placenta, liver, kidney, pancreas and skeletal muscle.

Pathways: Protein targeting to Nucleus