NFATC4 Antikörper (AA 480-530)

Produktnummer ABIN1386186

Produktdetails anti-NFATC4 Antikörper

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Bindungsspezifität: AA 480-530

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFATC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NF-ATc4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-NFATC4 Antikörper (ABIN1386186)

Xie, Deng, Pan, Ren, Jin, Wang, Wang, Zhu, Guo, Yuan, Shang, Liu: "Chronic intermittent hypoxia induces cardiac hypertrophy by impairing autophagy through the adenosine 5'-monophosphate-activated protein kinase pathway." in: Archives of biochemistry and biophysics, Vol. 606, pp. 41-52, (2016) (PubMed).

Details zu NFATC4

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Andere Bezeichnung: NF-ATc4 (NFATC4 Produkte)

Synonyme: si:dkeyp-66d1.4 antikoerper, NFATC4 antikoerper, 3110041H08Rik antikoerper, AW107667 antikoerper, AW546455 antikoerper, Nfat3 antikoerper, NF-ATc4 antikoerper, NFAT3 antikoerper, nuclear factor of activated T-cells 4 antikoerper, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 antikoerper, NFATC4 antikoerper, nfatc4 antikoerper, Nfatc4 antikoerper

Hintergrund:

Synonyms: NFAT3, NF-AT3, NF-ATC4, Nuclear factor of activated T-cells, cytoplasmic 4, NFATc4, T-cell transcription factor NFAT3

Background: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors, this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.

Gen-ID: 4776

UniProt: Q14934

Pathways: RTK Signalweg, WNT Signalweg