NDUFS7 Antikörper (AA 101-160)

Produktnummer ABIN1386126

Produktdetails anti-NDUFS7 Antikörper

Target: NDUFS7 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 7, 20kDa (NADH-Coenzyme Q Reductase) (NDUFS7))

Bindungsspezifität: AA 101-160

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDUFS7 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NDUFS7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NDUFS7

Target: NDUFS7 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 7, 20kDa (NADH-Coenzyme Q Reductase) (NDUFS7))

Andere Bezeichnung: NDUFS7 (NDUFS7 Produkte)

Synonyme: 1010001M04Rik antikoerper, CI-20 antikoerper, CI-20KD antikoerper, MY017 antikoerper, PSST antikoerper, NADH dehydrogenase (ubiquinone) Fe-S protein 7 antikoerper, NADH:ubiquinone oxidoreductase core subunit S7 antikoerper, Ndufs7 antikoerper, NDUFS7 antikoerper

Hintergrund:

Synonyms: CI 20, CI-20kD, Complex I 20 kDa subunit, Complex I mitochondrial respiratory chain 20 KD subunit, Complex I-20kD, MGC120002, MY017, NADH coenzyme Q reductase, NADH dehydrogenase ubiquinone Fe S protein 7 20 kDa NADH coenzyme Q reductase, NADH dehydrogenase ubiquinone FeS protein 7, 20 kDa NADHcoenzyme Q reductase, NADH dehydrogenase ubiquinone FeS protein7, 20 kDa NADHcoenzyme Q reductase, NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial, NADH-ubiquinone oxidoreductase 20 kDa subunit, NADH:ubiquinone oxidoreductase PSST subunit, NADHcoenzyme Q reductase, Ndufs7, NDUS7_HUMAN, PSST, PSST subunit.

Background: Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity. Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.