ELANE Antikörper (AA 101-200)

Produktnummer ABIN1386058

Produktdetails anti-ELANE Antikörper

Target: ELANE (Elastase, Neutrophil Expressed (ELANE))

Bindungsspezifität: AA 101-200

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELANE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Neutrophil Elastase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-ELANE Antikörper (ABIN1386058)

Li, Jia, Ji, Gong, Wang, Zhang, Wang, Zang: "The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats." in: International journal of molecular medicine, Vol. 38, Issue 3, pp. 767-75, (2016) (PubMed).

Maekawa, Ishijima, Ida, Izumo, Ono, Shibata, Abe: "Prophylactic Effect of Lactobacillus pentosus strain S-PT84 on Candida Infection and Gastric Inflammation in a Murine Gastrointestinal Candidiasis Model [Errata]." in: Medical mycology journal, Vol. 57, Issue 4, pp. E81-E92, (2016) (PubMed).

Jeffery, Kimura, Gray, Lueth, Bellaire, LeVine: "Dogs cast NETs too: Canine neutrophil extracellular traps in health and immune-mediated hemolytic anemia." in: Veterinary immunology and immunopathology, Vol. 168, Issue 3-4, pp. 262-8, (2015) (PubMed).

Details zu ELANE

Target: ELANE (Elastase, Neutrophil Expressed (ELANE))

Andere Bezeichnung: Neutrophil Elastase (ELANE Produkte)

Synonyme: ELA2 antikoerper, GE antikoerper, HLE antikoerper, HNE antikoerper, NE antikoerper, PMN-E antikoerper, SCN1 antikoerper, Ela2 antikoerper, F430011M15Rik antikoerper, ela2 antikoerper, ELANE antikoerper, elastase, neutrophil expressed antikoerper, proteinase 3 antikoerper, ELANE antikoerper, Elane antikoerper, prtn3 antikoerper

Hintergrund:

Synonyms: GE, NE, HLE, HNE, ELA2, SCN1, PMN-E, Neutrophil elastase, Bone marrow serine protease, Elastase-2, Human leukocyte elastase, Medullasin, PMN elastase, ELANE

Background: Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis.

Gen-ID: 1991

UniProt: P08246