PCSK2 Antikörper (AA 201-300)

Produktnummer ABIN1385997

Produktdetails anti-PCSK2 Antikörper

Target: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Bindungsspezifität: AA 201-300

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCSK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Proprotein Convertase 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-PCSK2 Antikörper (ABIN1385997)

van Rijn, Pouwer, Tryfonidou, Grinwis, van der Bend, Beukers, Vastenhout, Drouin, Penning, Meij: "Expression and clinical relevance of paired box protein 7 and sex determining region Y-box 2 in canine corticotroph pituitary adenomas." in: Veterinary journal (London, England : 1997), Vol. 204, Issue 3, pp. 315-21, (2015) (PubMed).

Details zu PCSK2

Target: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Andere Bezeichnung: Proprotein Convertase 2 (PCSK2 Produkte)

Synonyme: NEC 2 antikoerper, NEC-2 antikoerper, NEC2 antikoerper, PC2 antikoerper, SPC2 antikoerper, PCSK2 antikoerper, 6330411F23Rik antikoerper, AI839700 antikoerper, Nec-2 antikoerper, Nec2 antikoerper, Phpp-2 antikoerper, pc2 antikoerper, nec2 antikoerper, spc2 antikoerper, pcsk2 antikoerper, pcsk2-A antikoerper, proprotein convertase subtilisin/kexin type 2 antikoerper, proprotein convertase subtilisin/kexin type 2 L homeolog antikoerper, PCSK2 antikoerper, pcsk2 antikoerper, Pcsk2 antikoerper, pcsk2.L antikoerper

Hintergrund:

Synonyms: PC2, NEC2, SPC2, NEC 2, NEC-2, Neuroendocrine convertase 2, KEX2-like endoprotease 2, Prohormone convertase 2, Proprotein convertase 2, PCSK2

Background: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells.

Gen-ID: 5126

UniProt: P16519

Pathways: Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity