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UBE2D2 Antikörper (AA 31-130)

UBE2D2 Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1385976
  • Target Alle UBE2D2 Antikörper anzeigen
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    Bindungsspezifität
    • 14
    • 12
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-130
    Reaktivität
    • 59
    • 30
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 52
    • 7
    Kaninchen
    Klonalität
    • 53
    • 6
    Polyklonal
    Konjugat
    • 31
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBE2D2 Antikörper ist unkonjugiert
    Applikation
    • 53
    • 26
    • 12
    • 12
    • 8
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Cow,Sheep,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human UBE2D2
    Isotyp
    IgG
    Top Product
    Discover our top product UBE2D2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    Andere Bezeichnung
    UBE2D2 (UBE2D2 Produkte)
    Synonyme
    E2(17)KB2 antikoerper, PUBC1 antikoerper, UBC4 antikoerper, UBC4/5 antikoerper, UBCH5B antikoerper, 1500034D03Rik antikoerper, Ubc2e antikoerper, Ube2d2 antikoerper, ubc4 antikoerper, ube2d2 antikoerper, zgc:55886 antikoerper, E217kB antikoerper, ubiquitin conjugating enzyme E2 D2 antikoerper, ubiquitin-conjugating enzyme E2D 2A antikoerper, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) antikoerper, ubiquitin-conjugating enzyme E2D 2 antikoerper, ubiquitin conjugating enzyme E2 D3 antikoerper, UBE2D2 antikoerper, Ube2d2a antikoerper, ube2d2 antikoerper, Ube2d2 antikoerper, UBE2D3 antikoerper
    Hintergrund

    Synonyms: PUBC 1, PUBC1, UB2D2_HUMAN, UBC 4, UBC 4/5, UBC4, UBC4/5, UBC4/5 homolog yeast, UBCH 5B, UBCH5B, UBE2D2, Ubiquitin carrier protein, Ubiquitin carrier protein D2, Ubiquitin conjugating enzyme E2 17 kDa 2, Ubiquitin conjugating enzyme E2 D2, Ubiquitin conjugating enzyme E2D 2 homologous to yeast UBC4/5, Ubiquitin conjugating enzyme E2D 2 UBC4/5 homolog yeast, Ubiquitin conjugating enzyme E2D 2, Ubiquitin protein ligase D2, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin-conjugating enzyme E217KB 2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase D2, E217KB2.

    Background: Ubiquitin is an abundant, highly conserved protein found in all eukaryotic cells either free or covalently attached to cellular proteins. The primary function of ubiquitin in mammalian systems is to clear abnormal, foreign, and improperly folded proteins by targeting them for proteosome degradation. UBE2D proteins, including UBE2D1 (ubiquitin-conjugating enzyme E2D1 or UBC5A), UBE2D2 (ubiquitin-conjugating enzyme E2D2 or UBC5B) and UBE2D3 (ubiquitin-conjugating enzyme E2D3 or UBC5C), are E2 ubiquitin-conjugating enzymes that catalyze the ubiquitination of I˚,Bå, in a phosphorylation and SCFB-TRCP-dependent manner. Specifically, E1 first transfers a ubiquitin residue to the E2 component (a UBE2D protein), and the UBE2D protein then associates with an E3 ubiquitin-protein ligase, which immediately transfers that residue to a protein that is targeted for degradation.

    Gen-ID
    7322
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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